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Epitalon – 50mg

Epitalon (Epithalon) is a synthetic pineal tetrapeptide (Ala-Glu-Asp-Gly) studied in research for telomerase-pathway activity, pineal melatonin regulation, and cellular aging models.

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Certificate of Analysis

Verified purity data and more—third party tested by Freedom Diagnostics.

Verified Research Quality

Every batch of Epitalon supplied by Rejuven8 undergoes rigorous batch-specific analytical verification to confirm identity, purity, and net peptide content.

Rejuven8 Research Standard

≥99% Analytical Purity

Third-Party Analytical Testing

HPLC Verification

Mass Spectrometry Identity Confirmation

Batch-Specific Certificate of Analysis

Certificate of Analysis

Batch testing includes:

  • High-Performance Liquid Chromatography (HPLC)
  • Mass Spectrometry Identity Verification
  • Analytical Purity Confirmation

Epitalon Peptide Research Overview

Epitalon, also rendered as Epithalon or by its sequence designation AEDG, is a synthetic tetrapeptide (Ala-Glu-Asp-Gly) originally developed within the Khavinson short-peptide bioregulator program as a synthetic analog of the pineal extract epithalamin. In laboratory research, the Epitalon peptide is studied as a tool compound in models of telomere biology, pineal gland function, and age-associated cellular change.

Because of its short sequence and its history in the Russian bioregulator literature, Epitalon has become one of the most frequently referenced compounds in preclinical longevity-peptide research.

Preclinical investigations have explored Epitalon in experimental models studying:

  • telomerase activity and telomere-length dynamics
  • pineal melatonin synthesis and circadian signaling
  • chromatin condensation and gene-expression modulation
  • age-associated cellular senescence models
  • oxidative-stress and neuroendocrine regulation models

Mechanistic Research Insights

Experimental research examines Epitalon primarily through its reported effects on gene expression in cellular models, with particular attention to telomerase-related and neuroendocrine pathways.

Areas of investigation include:

  • expression of the telomerase catalytic subunit in somatic cell cultures
  • telomere elongation in human cell-line models
  • regulation of melatonin production in pinealocyte models
  • chromatin decondensation and transcription-factor accessibility
  • antioxidant-enzyme expression in aging research models

These mechanisms are commonly studied in cell cultures and preclinical aging models.

Compound Information

Compound Name: Epitalon (Epithalon)

Alternate Designations: Epithalon, Epithalone, AEDG Peptide

Peptide Class: Synthetic Pineal Tetrapeptide (Khavinson Bioregulator)

Sequence: Ala-Glu-Asp-Gly

Molecular Formula: C14H22N4O9

Molecular Weight: ~390.35 g/mol

CAS Number: 307297-39-8

Product Specifications

Purity: ≥99%

Testing Methods: HPLC & Mass Spectrometry

Appearance: Lyophilized white powder

CAS Number: 307297-39-8

Each batch undergoes analytical verification to confirm peptide identity, purity, and consistency.

Storage

For optimal stability, store lyophilized peptides in a cool, dry environment away from direct light. Long-term storage conditions may vary depending on laboratory requirements.

Research Use Notice

This compound is supplied strictly for laboratory research purposes only. Not intended for human consumption, therapeutic use, or veterinary use.

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