SS-31 – 10mg

Verified Research Quality

Every batch of SS-31 supplied by Rejuven8 undergoes rigorous batch-specific analytical verification to confirm identity, purity, and net peptide content.

Rejuven8 Research Standard

✓ ≥99% Analytical Purity
✓ Third-Party Analytical Testing
✓ HPLC Verification
✓ Mass Spectrometry Identity Confirmation
✓ Batch-Specific Certificate of Analysis

Certificate of Analysis

Batch testing includes:

• High-Performance Liquid Chromatography (HPLC)
• Mass Spectrometry Identity Verification
• Analytical Purity Confirmation

SS-31 Peptide Research Overview

SS-31, also designated elamipretide or MTP-131, is a synthetic mitochondria-targeting tetrapeptide of the Szeto-Schiller peptide class. In laboratory research, the SS-31 peptide is studied for its selective association with cardiolipin, a phospholipid concentrated in the inner mitochondrial membrane, and as a tool compound in models of mitochondrial bioenergetics and oxidative-stress signaling.

Because of its aromatic-cationic structure, SS-31 partitions into the inner mitochondrial membrane largely independent of membrane potential, which has made it a frequent reference compound in preclinical investigations of mitochondrial membrane biology.

Preclinical investigations have explored SS-31 in experimental models studying:

• cardiolipin-associated membrane organization
• electron-transport-chain and ATP-synthesis pathways
• reactive oxygen species (ROS) and oxidative-stress models
• age-associated mitochondrial function
• ischemia and reperfusion research models

Mechanistic Research Insights

Experimental research examines SS-31 through its interaction with cardiolipin in the inner mitochondrial membrane, with downstream effects studied across several bioenergetic pathways.

Areas of investigation include:

• stabilization of cardiolipin-protein interactions
• cristae membrane organization
• mitochondrial respiration and ADP sensitivity
• electron-transport-chain efficiency
• reactive oxygen species modulation

These mechanisms are commonly studied in isolated mitochondria and cellular models of energy metabolism.

Compound Information

Compound Name: SS-31 (Elamipretide)
Alternate Designations: MTP-131, Bendavia
Peptide Class: Mitochondria-Targeting Tetrapeptide (Szeto-Schiller)
Sequence: D-Arg-Dmt-Lys-Phe-NH2
Molecular Formula: C32H49N9O5
Molecular Weight: ~639.8 g/mol
CAS Number: 736992-21-5

Product Specifications

Purity: ≥99%
Testing Methods: HPLC & Mass Spectrometry
Appearance: Lyophilized white powder
CAS Number: 736992-21-5

Each batch undergoes analytical verification to confirm peptide identity, purity, and consistency.

Storage

For optimal stability, store lyophilized peptides in a cool, dry environment away from direct light. Long-term storage conditions may vary depending on laboratory requirements.

Research Use Notice

This compound is supplied strictly for laboratory research purposes only. Not intended for human consumption, therapeutic use, or veterinary use.